Research-Specific Grants

• Solicits investigator-initiated research proposals focused on the broad area of perioperative musculoskeletal pain management focused on, but not limited to the following areas:
• Perioperative pain management opioid-sparing research through varying pain control techniques using non-narcotic, multimodal options
• Determining the safest and most efficacious regional anesthesia techniques to provide benefit to patients undergoing orthopaedic operations, including, but not limited to, the assessment of patient reported outcomes as well as functional assessment
• Areas of research focus may include translational or clinical research to preferably include at least pilot human studies. The proposal should build upon the research principles and guidelines published in the supplement to the Journal of Bone and Joint Surgery entitled "Proceedings of the JBJS Pain Management Research Symposium" and published in May, 2020. Click here to view the supplement.
• Proposals will be adjudicated on scientific merit, feasibility, and an ability to effect positive change through an important scientific contribution. Publication of results in a leading peer reviewed journal is expected.
• Anticipated clinical impact of all proposals must be clearly noted in the abstract and specific aims and be obvious from the title and the study design. All proposed projects are expected to generate results that have a practical application.

• OREF/AANA Foundation requires a Certified Registered Nurse Anesthetist (CRNA) in the role of Principal Investigator (PI) or co-PI who may be collaborating with a PhD and/or MD in order to foster the application of a full range of expertise, approaches, technologies, and creativity. 
• A PhD may serve as the principal investigator (PI); if a CRNA serves as co-PI.  The CRNA serving as PI or co-PI must meet the requirements for Continuous Professional Certification by the National Board of Certification and Recertification for Nurse Anesthetists (NBCRNA). A PhD serving as PI or co-PI must hold a faculty appointment. An MD serving as co-PI must have a valid license to practice in the United States.  

• OREF encourages investigator-initiated research proposals focused on total joint replacement. Areas of research focus may include: New surgical techniques, devices, joint implant designs, joint implant materials, or the biology of disease and repair.

• OREF strongly encourages the submission of well-crafted basic, translational and clinical studies.
• Clinical relevance must be clearly noted in the abstract and specific aims and be obvious from the title and the study design. All proposed projects should generate results that have a practical application. It is expected that upon completion of the proposed project, the principal investigator will be well poised to pursue NIH/DOD or the equivalent large-scale funding to continue to advance the area of research.

• Domestic, non-profit, public, and private institutions of higher education, such as hospitals, medical schools, universities, and colleges.
• Multidisciplinary research activity is always encouraged. The principal investigator (PI) must be an orthopaedic surgeon or a full-time researcher (e.g., PhD, DVM, DO).  The orthopaedic surgeon must be licensed to practice and working in an institution in the United States. A PhD serving as PI or co-PI must hold a primary or secondary faculty appointment in an orthopaedic department. A letter from the department chair confirming this appointment is required.
• The PI must be a new investigator. A new investigator is classified as an individual who has not received an R01 National Institutes of Health (NIH) grant or its equivalent (e.g., VA, DOD, NSF) as a PI.
• NOTE: Letters of Intent—The first step in applying for this grant is to submit a Letter of Intent (LOI). To access the LOI submission instructions, click the button below and log in to proposalCENTRAL. If you do not have pC login credentials, click on the create an account link to setup your credentials. Next, click the Apply Now button (top-right) for the grant you wish to submit. The full RFA and LOI instructions can be found as downloadable documents in step 2, "download templates and instructions." 

• Soliciting investigator-initiated research proposals focused on the broad area of injectable orthobiologics for the treatment of knee osteoarthritis, including but not limited to the following areas:
• Determining clinical efficacy and safety of an injectable orthobiologic treatment(s) to provide decreased pain and improved function, preferably through the assessment of a balanced outcome scorecard measuring patient-reported outcomes and appropriate clinical outcomes.
• Assessing the mechanisms of action of an injectable orthobiologic treatment(s) in knee osteoarthritis to reduce pain and improve function or modify the progression of disease in patients with knee osteoarthritis.

• Orthopaedic Surgeons licensed to practice in the U.S and working in an institution in the U.S. with active clinical practice.
• Principal Investigator is required to be member of the American Academy of Orthopaedic Surgeons (AAOS).
• PhDs, DVMs or other qualified researchers can serve as a co-investigator, but should hold a faculty appointment in an orthopaedic department at an institution in the U.S.

•  This initiative addresses the need to support and facilitate research that can be completed within a limited time frame and budget.
• Competitive proposals should aim to help us better understand how to prevent and treat osteoarthritis, one of the most common causes of disability in adults.

• Applications may be submitted by domestic and non-profit, public and private institutions of higher education, such as hospitals, medical schools, universities, and colleges.
• Multidisciplinary research activity is always encouraged. A PhD or DVM may serve as the principal investigator (PI) if s/he has a primary or secondary faculty appointment in an orthopaedic department. A letter from the department chair confirming this appointment is required. The orthopaedic surgeon must be licensed to practice in the United States.
• NOTE: Letters of Intent—Deadline: December 10, 2020, 10:59 p.m. CST
  The first step in applying for this grant is to submit a Letter of Intent (LOI). To access the LOI submission instructions, click the button below and log in to proposalCENTRAL (pC). If you do not have pC login credentials, click on the create an account link to setup your credentials. Next, click the Apply Now button (top-right) for the grant you wish to submit. The full RFA and LOI instructions can be found as downloadable documents in step 2, "download templates and instructions."

• This Funding Opportunity Announcement solicits investigator-initiated research proposals to explore the impact of regulatory practices on the patient-physician relationship. The proposal should examine how and to what extent the burden of additional required documentation impacts the amount and quality of time a physician has available to focus on direct patient care.
• Examples of areas of investigation can include:
  
  • Clarifying impact of the EMR “copy and pasting” practice on the utility of the EMR for clinical decision making
  • Documenting the impact of examination room computer documentation on physician-patient communication
  • Assessing the impact of medical “ scribes” on physician-patient communication
  • Examining the impact of EMR documentation on the process of shared decision making
  • Detailing potential EMR practice changes to enhance the utility of the EMR for clinical research
  • The impact of the EMR on physician well-being, burn out/ attrition, and job satisfaction.
  • The impact of other bureaucratic, administrative and regulatory mandates on the physician-patient relationship and/or physician well-being and job satisfaction
• Submitted proposals should seek to gain a better understanding of whether regulatory policies such as those related to documenting patient encounters in an electronic medical record (EMR) system enhances or erodes the doctor patient relationship, patient satisfaction and patient safety.

 

• Applications may be submitted by non-profit, public and private institutions of higher education, such as hospitals, medical schools, universities, and colleges, in the United States. 
• Multidisciplinary research activity is always encouraged.  PhDs may serve as the principal investigator (PI) if they have a primary or secondary faculty appointment in an orthopaedic department.  A letter from the department chair confirming this appointment is required. The orthopaedic surgeon must be licensed to practice in the United States.
• The orthopaedic surgeon must provide a statement on time to be allocated to the project indicating percent of average time allocated and how the time will be spent.
• The Principal Investigator must be a new investigator.  A new investigator is classified as an individual who has not received an R01 National Institutes of Health (NIH) grant or its equivalent (e.g., VA, DOD, and NSF, etc.) as a PI. New investigators who have demonstrated a sustained interest in research and excellence in their training are encouraged to apply.
• Applicants are limited to one submission to OREF per cycle regardless of category. The same project may not be submitted in multiple categories, even if the PI is different. The principal investigator may receive only one OREF grant of each type during his/her lifetime.

• Areas of research focus include the following, although other areas of disparity in orthopaedic practice will be considered:
• Strategies to reduce racial/ethnic inequities in Orthopaedic treatment
• Disproportionate outcomes/access to care for minority Orthopaedic patients
• Diversity in Orthopaedic Surgical Training
• To Access the Request for Application, you will need a proposalCENTRAL account.  If you don’t already have one, go to proposalCENTRAL by clicking the button below, then click the “Create an Account” link, which is in the top right corner of the page.

• Orthopaedic surgeons licensed to practice and working at an institution in the United States or Canada
• The PI or Co-PI must be active members of the J. Robert Gladden Society.
• New, early stage and established investigators are eligible to apply

• Encourages new investigators by providing seed and start-up funding for promising research projects that address issues related to the treatment of arthritis with an emphasis on arthroplasty. 
• Clinical relevance must be clearly noted in the abstract and specific aims, and be obvious from the title and the study design.
• All proposed projects should generate results that have a practical application. It is expected that upon completion of the proposed project, the principal investigator will be well poised to pursue NIH/DOD or the equivalent large-scale funding to continue to advance the area of research.

• Domestic, non-profit, public and private institutions of higher education, such as hospitals, medical schools universities, and colleges.
• An orthopaedic surgeon principal investigator (PI) who is licensed to practice in and working in an institution in the United States. A PhD may serve as the PI but must hold a faculty appointment in an orthopaedic department at an institution in the United States. A letter from the department chair confirming the appointment is required. A DVM may serve as the PI, but must have a primary appointment in an orthopaedic department. Listing an orthopaedic surgeon as the co-principal investigator is required. A letter from the department chair confirming the appointment is also required.
• The PI must be a new investigator. A new investigator is classified as an individual who has not received an R01 National Institutes of Health (NIH) grant or its equivalent (e.g., VA, DOD, NSF) in the role of PI.
• An orthopaedic resident cannot apply without documentation that he/she will be starting a staff/faulty appointment at the time the grant commences (a letter from the chair of the new department must be included).

To find out when this opportunity will be available, please click here. Please note that dates are subject to change and the website will be updated accordingly.

Investigators are invited to apply in one of two available categories:

• $225,000 Career Development Grant (disbursed over a three year period)
• $150,000 Career Development Grant (disbursed over a two year period)
This funding opportunity solicits investigator-initiated multidisciplinary research proposals focused on the development of new cell and tissue-based strategies to prevent, repair, regenerate, or replace injured musculoskeletal tissues.
• To Access the LOI instructions, you will need a proposalCENTRAL account. If you don't already have one, go to proposalCENTRAL by clicking the button below, then click the "Create an Account" link, which is located in the top right corner of the page.

• Domestic non-profit, public and private institutions
• OREF requires an Orthopaedic Surgeon in the role of PI or co-PI collaborating with a PhD
• A PhD may serve as the principal investigator (PI) if an orthopaedic surgeon serves as co-PI

• Grant period: 2-3 years (commencing January 2019)
• The objective of this grant is to provide startup funding or seed money for a new investigator conducting clinical/and or social research in the prevention of musculoskeletal youth sports injuries.
• Clinical relevance must be clearly noted in the abstract and specific aims and be obvious from the title and the study design.
• All proposed projects are expected generate results that have practical application.
• OREF will fund only one Prevention of Musculoskeletal Youth Sports Injuries Grant per institution per year.
• Please note: Although the potential for concussions and their harmful impact on young athletes is a major issue for the field of pediatrics and sports medicine, this topic is not within the scope of this grant program.  Accordingly, no proposed projects regarding youth concussions will be considered.

• The orthopaedic surgeon must provide a statement on time to be allocated to the project indicating percent of average time allocated and how the time will be spent.

• Applications may be submitted by domestic and Canadian non-profit, public and private institutions of higher education, such as hospitals, medical schools, universities, and colleges. 
• Multidisciplinary research activity is always encouraged.  PhDs and DVMs may serve as the principal investigator (PI) if they have a primary or secondary faculty appointment in an orthopaedic department.  A letter from the department chair confirming this appointment is required. The orthopaedic surgeon must be licensed to practice in the United States.
• The orthopaedic surgeon must provide a statement on time to be allocated to the project indicating percent of average time allocated and how the time will be spent.
• The Principal Investigator must be a new investigator.  A new investigator is classified as an individual who has not received an R01 National Institutes of Health (NIH) grant or its equivalent (e.g., VA, DOD, and NSF, etc.) as a PI.
• Applicants are limited to one submission to OREF per cycle regardless of category. The same project may not be submitted in multiple categories, even if the PI is different. The principal investigator may receive only one OREF grant of each type during his/her lifetime.
• NOTE: Letters of Intent—The first step in applying for this grant is to submit a Letter of Intent (LOI). To access the LOI submission instructions, click the button below and log in to proposalCENTRAL. If you do not have pC login credentials, click on the create an account link to setup your credentials. Next, click the Apply Now button (top-right) for the grant you wish to submit. The full RFA and LOI instructions can be found as downloadable documents in step 2, "download templates and instructions." 

• OREF, in partnership with the Orthopaedic Trauma Association (OTA), encourages investigator-initiated research proposals focusing on Orthopaedic Trauma. For a list of suggested trauma topics, please view the application on proposalCENTRAL
• Highlighted areas of research focus include the following:
o Registries to identify variable in cost and outcomes after treatment of common fractures and to determine factors that re predictive of function and health-related quality of life. 
o  Infection prevention after fracture fixation using local and systemic therapies (i.e. skin preparation agents, antibiotics and wound management modalities).
o Multi-disciplinary team approach to improve outcomes in fracture care, including hip fractures and major extremity trauma
• Clinical relevance of all proposals must be clearly noted in the abstract and specific aims and be obvious from the title and the study design.
• All proposed projects are expected to generate results that have a practical application. It is expected that upon completion of the proposed project, the principal investigator will be well poised to pursue NIH/DOD or the equivalent large-scale funding to continue to advance the area of research.

• Applications may be submitted by domestic, non-profit, public and private institutions of higher education, such as hospitals, medical schools, universities, and colleges.
• An orthopaedic surgeon principal investigator (PI) must be licensed to practice in the United States and working in an institution in the U.S. or Canada. PhDs or DVMs working in or holding a primary appointment at an institution/orthopaedic department in the U.S. or Canada may serve as the PI.  A letter from the department chair confirming the appointment is also required.
• The orthopaedic surgeon must provide a statement on time to be allocated to the project indicating percent of average time allocated and how time will be spent.
• Either the PI or Co-PI must be a member in good standing of the Orthopaedic Trauma Association (OTA). 
• Applicants are limited to one submission to OREF per cycle regardless of category.  The same project may not be submitted in multiple categories, even if the PI is different. The principal investigator may receive only one OREF grant of each type during his/her lifetime.
• NOTE: Letters of Intent—The first step in applying for this grant is to submit a Letter of Intent (LOI). To access the LOI submission instructions, click the button below and log in to proposalCENTRAL. If you do not have pC login credentials, click on the create an account link to setup your credentials. Next, click the Apply Now button (top-right) for the grant you wish to submit. The full RFA and LOI instructions can be found as downloadable documents in step 2, "download templates and instructions." 

•  This initiative addresses the need to support and facilitate cutting edge research that can be completed within a limited timeframe and budget.
• Competitve proposals should focus on robotic-assisted surgery for primary total hip arthroplasty
• The submission of well-crafted clinical studies that seek to quantify robotic-assisted patient outcomes in hip arthroplasty are strongly encouraged.
• New investigators who have demonstrated a sustained interest in research and excellence in their training are encouraged to apply
• Clinical relevance must be clearly noted in the abstract and specific aims and be obvious from the title and the study design.
• All proposed projects are expected to generate results that have a practical application.
• It is expected that upon completion of the proposed project, the principal investigator will be poised to pursue NIH/DOD or the equivalent large-scale funding to continue to advance the area of research.
• Maximum funding will be a total of $90,000 over a two-year grant period.

• Applications may be submitted by domestic and Canadian non-profit, public and private institutions of higher education, such as hospitals, medical schools, universities, and colleges. 
• Multidisciplinary research activity is always encouraged.  PhDs and DVMs may serve as the principal investigator (PI) if they have a primary or secondary faculty appointment in an orthopaedic department.  A letter from the department chair confirming this appointment is required. The orthopaedic surgeon must be licensed to practice in the United States
• The orthopaedic surgeon must provide a statement on time to be allocated to the project indicating percent of average time allocated and how the time will be spent.
• The Principal Investigator must be a new investigator.  A new investigator is classified as an individual who has not received an R01 National Institutes of Health (NIH) grant or its equivalent (e.g., VA, DOD, and NSF, etc.) as a PI.
• Applicants are limited to one submission to OREF per cycle regardless of category. The same project may not be submitted in multiple categories, even if the PI is different. The principal investigator may receive only one OREF grant of each type during his/her lifetime.
• NOTE: Letters of Intent—The first step in applying for this grant is to submit a Letter of Intent (LOI). To access the LOI submission instructions, click the button below and log in to proposalCENTRAL. If you do not have pC login credentials, click on the create an account link to setup your credentials. Next, click the Apply Now button (top-right) for the grant you wish to submit. The full RFA and LOI instructions can be found as downloadable documents in step 2, "download templates and instructions." 

• This initiative addresses the need to support and facilitate cutting edge research that can be completed within a limited time frame and budget.
• Competitive proposals should focus on total ankle replacement.
• The submission of well-crafted clinical and translational studies is strongly encouraged.
• New investigators who have demonstrated a sustained interest in research and excellence in their training are encouraged to apply
• Example areas of investigation include:
       • Revision TAR - Revision of failed primary ankle arthroplasty or arthrodesis
          into TAR
       • Minimally Invasive Surgery (MIS) in Foot and Ankle
        •Total Ankle Replacement-Patient Specific Instrumentation
• Clinical relevance must be clearly noted in the abstract and specific aims and be obvious from the title and the study design.
• All proposed projects are expected to generate results that have a practical application
• It is expected that upon completion of the proposed project, the principal investigator will be poised to pursue NIH/DOD or the equivalent large-scale funding to continue to advance the area of research.
• Maximum funding will be a total of $72,000 over a two-year grant period

• Applications may be submitted by domestic and Canadian non-profit, public and private institutions of higher education, such as hospitals, medical schools, universities, and colleges. 
• Multidisciplinary research activity is always encouraged.  PhDs and DVMs may serve as the principal investigator (PI) if they have a primary or secondary faculty appointment in an orthopaedic department.  A letter from the department chair confirming this appointment is required. The orthopaedic surgeon must be licensed to practice in the United States.
• The orthopaedic surgeon must provide a statement on time to be allocated to the project indicating percent of average time allocated and how the time will be spent
• The Principal Investigator must be a new investigator.  A new investigator is classified as an individual who has not received an R01 National Institutes of Health (NIH) grant or its equivalent (e.g., VA, DOD, and NSF, etc.) as a PI.
• Applicants are limited to one submission to OREF per cycle regardless of category. The same project may not be submitted in multiple categories, even if the PI is different. The principal investigator may receive only one OREF grant of each type during his/her lifetime.
• NOTE: Letters of Intent—The first step in applying for this grant is to submit a Letter of Intent (LOI). To access the LOI submission instructions, click the button below and log in to proposalCENTRAL. If you do not have pC login credentials, click on the create an account link to setup your credentials. Next, click the Apply Now button (top-right) for the grant you wish to submit. The full RFA and LOI instructions can be found as downloadable documents in step 2, "download templates and instructions." 

• OREF, in partnership with Stryker, encourages proposals in support of cutting edge research that focuses on robotic-assisted surgery for primary total knee arthroplasty.
• Well-crafted clinical studies that seek to quantify robotic-assisted patient outcomes in knee arthroplasty are strongly encouraged.
• Clinical relevance must be clearly noted in the abstract and specific aims and be obvious from the title and the study design.
• Proposed projects are expected to generate results that have a practical application.

• The Principal Investigator must be a new investigator.  A new investigator is classified as an individual who has not received an R01 National Institutes of Health (NIH) grant or its equivalent (e.g., VA, DOD, and NSF, etc.) as a PI.  New investigators who have demonstrated a sustained interest in research and excellence in their training are encouraged to apply.
• Applications may be submitted by domestic or Canadian non-profit, public and private institutions of higher education, such as hospitals, medical schools, universities, and colleges.    
• PI or co-PI must be an orthopaedic surgeon licensed to practice in the United States and working in an institution in the U.S.
• PhDs or DVMs are eligible if working in or holding a primary or secondary appointment at an institution/orthopaedic department in the United States or Canada.

• OREF in partnership with American Shoulder and Elbow Surgeons (ASES) and Dr. Charles Rockwood encourages new investigators to conduct research in the area of shoulder care.
• Focus is clinical research. Clinical relevance must be clearly noted in the abstract and specific aims and be obvious from the title and study design.
• To Access the Request for Application, you will need a proposalCENTRAL account. If you don't already have one, go to proposalCENTRAL by clicking the button below, then click the "Create an Account" link, which is located in the top right corner of the page.

• PI or Co-PI must be an orthopaedic surgeon.
• PhDs and DVMs are eligible if affiliated with an orthopaedic department
• PI/Co-PI must be an ASES member.