$500,000+ in New Funding Available
Applications are now available for OREF signature grants, pain management research, support for NIH K Award recipients and a new opportunity for early-stage investigators.
07-09-2025 | Updated: 7-10-2025
OREF is pleased to announce the availability of more than $550,000 in new funding. Applications are now available for OREF signature grants, pain management research, support for NIH K Award recipients and a new opportunity for early-stage investigators. View RFAs on ProposalCentral for complete eligibility requirements and instructions. Please note, ProposalCentral requires you to log in to see available opportunities.
Letters of Intent
Letters of Intent (LOIs) must be completed for the following grants. All properly submitted LOIs will be reviewed by the Research Committee. If your LOI is selected to advance, you will be invited to complete a full proposal.
OREF Signature Grants
LOIs due August 11, 2025
These longstanding programs are at the heart of OREF’s commitment to supporting investigators throughout their careers. Investigators from residency to those who’ve made a commitment to scientific research are encouraged to apply.
- Career Development Grant provides $300,000 in funding over three years to encourage investigators to commit to scientific research. Research may be basic, translational, clinical and/or health services.
- New Investigator Grant provides $50,000 to advance the scientific training of the next generation of orthopaedic physician-scientists with seed and start-up funding for promising research projects. Residents, fellows, and orthopaedic surgeons having completed formal training within the last four years may apply.
New and Additional Opportunities
LOIs due August 11, 2025
- NEW! OREF/John W. Brown Early-Stage Investigator Enabling Technologies in Musculoskeletal Care Research Grant provides $100,000 for research that will address the use of enabling technologies in musculoskeletal health care.
- OREF Multimodal Musculoskeletal Perioperative Pain Management Grant in collaboration with the American Association of Nurse Anesthetists (AANA) Foundation provides $92,500 in funding for research focused on the broad area of perioperative musculoskeletal pain management.
No LOIs required. Applications due October 14, 2025
- Mentored Clinician Scientist Grant provides $20,000 for the development of new clinician scientists who have demonstrated success as both a clinician and a researcher. Allows investigators to spend dedicated time in research for a period of up to five years to develop a long and productive career in academic surgery.
Award Opportunities
Deadlines indicated below.
Click links for information on how to submit manuscripts and nominations
- OREF Clinical Research Award recognizes outstanding clinical research related directly to musculoskeletal disease or injury. Manuscripts should represent a large body of cohesive scientific work generally reflecting years of investigation. Manuscripts due August 31, 2025.
- ORS/OREF Distinguished Investigator Award honors an individual who has significantly contributed to the field of orthopaedic research, to the ORS and the OREF through their outstanding scientific achievements and their commitment of time and service Nominations due September 12, 2025.
