Research-Specific Grants

Highlighted areas of research focus include the following, although other areas of stem cell therapy may be considered:

• Stem cell therapy approaches for treating musculoskeletal conditions including but not limited to bone, cartilage, intervertebral disc, tendon, ligament, meniscus, muscle, etc.
• Tissue-specific or adult stem cell and related technology therapies (e.g., mesenchymal, adipose-derived, or muscle stem cells).
• Advancing the development of tissue-engineering, regenerative medicine, cellular, or pharmacologic technologies that focus on stem cell therapies for late stage translational or early stage clinical studies.
• Prospective, randomized, and controlled clinical trial to prove or disprove the efficacy of a stem cell therapy for musculoskeletal conditions.
• Clinical relevance must be clearly noted in the abstract and specific aims and be obvious from the title and the study design.
• Proposed projects are expected to generate results that have a practical application.

• Applications may be submitted by domestic or Canadian non-profit, public and private institutions of higher education, such as hospitals, medical schools, universities, and colleges.
• If the PrincipaI Investigator (PI) is an orthopaedic surgeon, he/she must hold a primary appointment in an orthopaedic surgery department, work in an institution in the U.S. or Canada, and be licensed to practice in the United States. If the PI is a PhD or DVM, he/she must hold a primary or secondary appointment at an institution/orthopaedic department in the U.S. or Canada. A letter from the department chair confirming the appointment is also required.
• If the PI is an orthopaedic surgeon, he or she must provide a statement on time to be allocated to research, indicating percent of time allocated to this project and how time will be spent.

NOTE: The first step in applying for this grant is to submit a Letter of Intent (LOI), following the instructions provided on ProposalCentral. All properly submitted LOIs will be reviewed by OREF. If your LOI is selected to advance, you will be invited to complete a full proposal.