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OREF/AAOS Clinical Gaps Research Fund

Providing patients with safe, proven, effective treatment options is the goal of every orthopaedic surgeon, but there are areas of practice where clarity does not exist because clinical data is not available. A lack of clear, unbiased data can make it challenging to convince a patient that a particular therapy may be the best option or to educate patients about therapies for which efficacy has not been established. Through a partnership between the AAOS and OREF, you can help close those data gaps.

About the Clinical Gaps Research Grant Program

  • OREF will administer these grants through its peer-review grant process. Applications for the fourth grant funded through this program are due by February 8, 2024. Learn more here.
  • A primary objective of funded studies will be determining clinical efficacy and safety of injectable orthobiologic treatments to provide decreased pain and improved function.
  • Studies will also seek to assess the mechanisms of action of injectable orthobiologic treatments in knee osteoarthritis to reduce pain and improve function or modify the progression of disease in patients with knee osteoarthritis.

Make a Clinical Gaps Research Fund Gift


Clinical Gaps Research

Apply Now: $50,000 OREF/AAOS Clinical Gaps Research Grant

Grant will fund research proposals focused on the broad area of injectable orthobiologics for the treatment of knee osteoarthritis. Click for more information.

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