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 "Our research program is designed to address the question of just how bones heal. We focus on this question at the molecular level; that is, which genes are responsible for stimulating the healing response? The answers are oftentimes surprising as we gain a deeper appreciation for the roles that certain proteins play in this process of skeletal repair."
Jill A. Helms, D.D.S., Ph.D.
1998 Recipient
Directed Research Grant
For information on how to apply for OREF Grants and Awards, please call or e-mail:
Jean McGuire
Vice President, Grants/CFO
(847) 384-4348
mcguire@oref.org
Mary Marino
Grants Administrator
(847) 384-4359
marino@oref.org
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2009 Grants and Awards Funded
CAREER DEVELOPMENT AWARD
Matthew B. Dobbs, M.D.
Washington University
Characterization of PITX1 in Mendelian and Complex
Inherited Lower Limb Malformations
Funded by the Dr. Dane and Mrs. Mary Louise Miller Endowment Fund
STRYKER CAREER
DEVELOPMENT AWARD
Nelson Fong SooHoo, M.D.
University of California, Los Angeles
Variation in the Quality of Care Delivered to Patients
Undergoing Total Joint Replacement
Funded by Stryker
RESEARCH GRANT
Francis H. Shen, M.D.
University of Virginia
A Novel Scaffold for Human Adipose-derived
Mesenchymal Cells: An Alternative Allograft for Spine Fusions
Funded by the Musculoskeletal Transplant Foundation
OREF/ASES ROCKWOOD
CLINICAL RESEARCH AWARD
Matthew L. Ramsey, M.D.
Rothman Institute, Thomas Jefferson University
Incidence and Risk Factors for Venous Thromboembolic
Disease Following Shoulder and Elbow Arthroplasty
Funded by the Dr. and Mrs. Charles Rockwood
Family Endowment Fund
OREF/POSNA RESEARCH GRANT
Paul Saluan, M.D.
Cleveland Clinic
Clinically Relevant Outcome Questionnaire for Adolescent
Patients with Pain or Injury in Upper and Lower Extremities
OREF CLINICAL AWARD
Lawrence C. Hurst, M.D.
State University of New York at Stony Brook
Injectable Clostridial Collagenase: Striving Toward Nonoperative
Treatment Options for Fibroproliferative Disorders
RESIDENT CLINICIAN SCIENTIST
TRAINING GRANTS
Jonathan C. Barnwell, M.D.
Wake Forest University
Glial-derived Neurotrophic Factor (GDNF) Delivery
using a Keratin-based Hydrogel for Enhanced Peripheral
Nerve Regeneration
Funded by DePuy Orthopaedics, Inc.
David M. Bear, M.D.
University of Pittsburgh
Detection of Subclinical Cartilage Injury Using
Optical Coherence Tomography (OCT)
Funded by the Ira A. Roschelle Family Foundation
Franklin K. Gettys, M.D.
Carolinas Medical Center
Cellular Origin and Gene Expression Pattern of
Methacrylate Induced Biomembranes
CORR / Association of Bone and Joint Surgeons
Resident Clinician Scientist Training Grant
Funded by the Association of Bone and Joint Surgeons
Carolyn M. Hettrich, M.D.
Hospital for Special Surgery
The Role of Mechanical Loading in Tendon to Bone Healing
Funded by DePuy Orthopaedics, Inc.
Xinning Li, M.D.
University of Massachusetts
Elastomeric Osteoconductive Bone Graft for the Repair
of Critical-sized Femoral Defects in Rats
Recipient of the MTF/Charles H. Herndon
Resident Clinician Scientist Training Grant
Funded by the Musculoskeletal Transplant Foundation
Rowena McBeath, M.D., Ph.D.
Washington University
The Role of Rac1 GTPase in Human Chondrocyte Dedifferentiation
Recipient of the MTF/Charles H. Herndon
Resident Clinician Scientist Training Grant
Funded by the Musculoskeletal Transplant Foundation
Sakkapol Ongwijitwat, M.D., Ph.D.
University of California, San Diego
Degeneration and Restoration of Trapeziometacarpal Cartilage
Funded by DePuy Orthopaedics, Inc.
Beatrice Shu, M.D.
Stanford University
Are Gait Changes Related to the Genesis of Osteoarthritis
and Can They be Changed with Surgical Intervention:
A Study of Coxarthrosis and Femoracetabular Impingement
Funded by the Ira A. Roschelle Family Foundation
Susan Shih-Han Tseng, M.D.
University of California, Davis
A Comparison of Adipose-derived and Bone Marrow-derived
Mesenchymal Stem Cells in the Prevention of a Rat Atrophic
Nonunion Model
Funded by DePuy Orthopaedics, Inc.
Sarah R. Zawodny, M.D.
University of Virginia
Osteotropic Peptides: Therapy for Surgically Induced Osteonecrosis
Funded by DePuy Orthopaedics, Inc.
STATE SOCIETY LECTURESHIPS
Arkansas Orthopaedic Society
Georgia Orthopaedic Society
Maryland Orthopaedic Association
North Carolina Orthopaedic Association
Pennsylvania Orthopaedic Society
Virginia Orthopaedic Society
HARK LECTURESHIPS
Clinical Orthopaedic Society
Eastern Orthopaedic Association
Mid-America Orthopaedic Association
Mid-Central States Orthopaedic Society
Rush University
Southern Orthopaedic Association
University of Virginia
Western Orthopaedic Association
EDUCATIONAL AWARD
American Academy of Orthopaedic Surgeons
2009 AAOS/ORS Clinical Trials in Orthopaedics
Research Symposium
JBJS RESIDENT JOURNAL CLUB GRANTS
Funding for 50 programs at a minimum of
$2,000 each for the 2009 2010 Academic Year
MISCELLANEOUS GRANTS
American Academy of Orthopaedic Surgeons
AAOS/OREF/ORS Clinician Scientist Development Program
American Orthopaedic Association
2009 AOA-OREF Zimmer Resident Leadership Forum
Journal of Bone and Joint Surgery
Web-based Educational Enhancements of Peer-reviewed
Scientific Articles
ORS/OREF Grant Writing Workshop
ORS Meeting in Las Vegas, February 21, 2009
ORS/OREF/AAOS Grant Writing Workshop
May 16 & 17, 2009 in Orlando, Fla.
United States Bone and Joint Decade
Young Investigator Initiative
2008 Grants and Awards
Funding Renewed for 2009
CLINICIAN SCIENTIST AWARD
Jennifer M. Wolf, M.D.
University of Colorado at Denver
Does Relaxin Mediate Gender Differences in Joint Laxity
and Osteoarthritis of the Thumb Carpo-metacarpal Joint?
Funded by the Dr. Zachary and Mrs. Kathleen Friedenberg
Endowment Fund
CAREER DEVELOPMENT AWARD
Mathias P. G. Bostrom, M.D.
Hospital for Special Surgery
Enhancing Cancellous Bone Formation via
Mechanical Loading and Parathyroid Hormone
Recipient of the Thomas M. Coffman Career Development Award
Funded by Stryker
RESEARCH GRANTS
Joseph A. Abboud, M.D.
University of Pennsylvania
The Effect of Hypercholesterolemia on Tendons
Funded through the support of
the Orthopaedic Surgeons Network of Arizona
Wael K. Barsoum, M.D.
Cleveland Clinic
Analysis of Dislocation Following Femoral Resurfacing
and Total Hip Replacement Using a Robotics Model
Boris Bershadsky, Ph.D.
Cleveland Clinic
Musculoskeletal Extension of a Generic Health-related
Quality of Life (QOL) Questionnaire
Funded by the Dr. Dane and Mrs. Mary Louise Miller Endowment Fund
Mark A. Frankle, M.D.
Florida Orthopaedic Institute Research Foundation
Range of Motion and Range-specific Strength
After Shoulder Arthroplasty
Funded by the Dr. Dane and Mrs. Mary Louise Miller Endowment Fund
Louis G. Jenis, M.D.
New England Baptist Hospital
Modulation of the Local Gene Expression Environment
within the Developing Spinal Fusion Mass with RNA
Interference Delivered by Gene Therapy
Funded by the Musculoskeletal Transplant Foundation
Joonyung Lee, M.D.
University of Pittsburgh
A Novel Genetic Model of Accelerated Aging to Study the
Cellular and Molecular Processes of Intervertebral Disc Aging
Xuhui Liu, M.D.
University of California, San Francisco
Role of MMP-2 and its Transcriptional Regulation in
Disuse-induced Skeletal Muscle Atrophy
Funded through the support of the Illinois Bone and Joint Institute
Arivalagan Muthusamy, Ph.D.
Pennsylvania State University
Regulation of Synovial Angiogenesis by
Perlecan in Rheumatoid Arthritis
Funded by the Dr. Victor and Mrs. Harriet Goldberg Endowment Fund
Steven J. Svoboda, M.D.
Keller Army Community Hospital
Changes in Serum Biomarkers for Cartilage Turnover
Following ACL Injury and Their Relationship to the
Development of Osteoarthritis
Shang-You Yang, M.D.
Wayne State University
Periprosthetic Cell Trafficking in Debris-associated Osteolysis
Funded through the support of the Hospital for Special Surgery
PROSPECTIVE CLINICAL
RESEARCH GRANTS
Laurence D. Higgins, M.D.
Brigham and Women’s Hospital
Rotator Cuff Arthropathy: Role of Vitamin D Status
Alec C. Stall, M.D.
University of Maryland, Baltimore
A Double-blind, Randomized Controlled Trial to Determine
the Effectiveness of Perioperative Hyperoxygenation in the
Prevention of Surgical Site Infections of the Lower Limb
POSNA/OREF RESEARCH GRANT
Kenneth M. Kozloff, Ph.D.
University of Michigan
Treatment of Disuse Osteopenia with Bisphosphonates
in Growing Bone — Differential Deposition and Healing
in Cortical and Cancellous Bone
2007 Grants and Awards
Funding Renewed for 2009
CLINICIAN SCIENTIST AWARDS
Cristin M. Ferguson, M.D.
Wake Forest University
Biologic Meniscus Replacement Using Decellularized Meniscus
Allograft Scaffolds: In Vivo Investigation of Seeded and Unseeded
Scaffolds in a Sheep Model
Funded by the Journal of Bone and Joint Surgery
Francis H. Shen, M.D.
University of Virginia
Molecular and Tissue Engineering: A Basis for Therapeutics
in Spine Surgery
Funded by the Dr. Dane and Mrs. Mary Louise Miller Endowment Fund
CAREER DEVELOPMENT AWARDS
Leesa M. Galatz, M.D.
Washington University
The Role of the Stress Environment on Formation of the
Tendon-bone Insertion Site — Development and Healing Models
Funded by Stryker
Young-Jo Kim, M.D., Ph.D.
Children’s Hospital, Boston
The Osteoarthritis Disease Modifying Potential of
Periacetabular Osteotomy for Hip Dysplasia
Recipient of the Thomas M. Coffman Career Development Award
Funded by the Dr. Dane and Mrs. Mary Louise Miller Endowment Fund,
World Arthrosis Organization, American Arthritis Society, The Hip Society, and Innovation Sports/ OSSUR |
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