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Grants and Awards

Research-Specific Grants

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  • OREF/ASES/Rockwood Clinical Research Grant in Shoulder Care

    $50,000 grant (Directed program)
    • OREF in partnership with American Shoulder and Elbow Surgeons (ASES) and Dr. Charles Rockwood encourages new investigators to conduct research in the area of shoulder care.
    • Focus is clinical research. Clinical relevance must be clearly noted in the abstract and specific aims and be obvious from the title and study design.
    • To Access the Request for Application, you will need a proposalCENTRAL account. If you don't already have one, go to proposalCENTRAL by clicking the button below, then click the "Create an Account" link, which is located in the top right corner of the page.
    • PI or Co-PI must be an orthopaedic surgeon.
    • PhDs and DVMs are eligible if affiliated with an orthopaedic department
    • PI/Co-PI must be an ASES member.
    The application period is closed.
    Sep 15, 2017, 10:59 PM
  • MTF Research Grant

    $98,000 grant ($49,000 per year) (Directed program)
    • OREF in partnership with the Musculoskeletal Transplant Foundation (MTF) offers seed money for new investigators conducting research on biologic skeletal reconstruction, including implants and stem cells.
    • Research may be basic or clinical.
    • Clinical relevance must be clearly noted in the abstract and specific aims and be obvious from the title and study design.
    • To Access the Request for Application, you will need a proposalCENTRAL account. If you don't already have one, go to proposalCENTRAL by clicking the button below, then click the "Create an Account" link, which is located in the top right corner of the page.
    • PI or Co-PI must be an orthopaedic surgeon. 
    • PhDs and DVMs are eligible if affiliated with an orthopaedic department
    The application period is closed.
    Sep 15, 2017, 10:59 PM
  • OREF Soft Tissue Repair and Regeneration Sports Medicine Grant In Honor of Russell F. Warren, MD [In collaboration with the American Orthopaedic Society for Sports Medicine (AOSSM)]

    $150,000 to $225,000 ($75,000 per year)
    OREF thanks everyone who contributed to the Warren Mentor Campaign for making this grant possible.

    Investigators are invited to apply in one of two available categories:

    • $225,000 Career Development Grant (disbursed over a three year period)
    • $150,000 Career Development Grant (disbursed over a two year period)
    • This funding opportunity solicits investigator-initiated multidisciplinary research proposals focused on the development of new cell and tissue-based strategies to prevent, repair, regenerate, or replace injured musculoskeletal tissues.
    • Letters of Intent (LOI)—A letter of intent is required for the OREF Soft Tissue Repair and Regeneration Sports Medicine Grant. Letters of Intent are due November 13, 2017 and can be submitted via proposalCENTRAL. Applicants invited to submit full proposals will be notified on Wednesday, December 13, 2017 by 10:59 p.m. U.S. Central Time
    • To Access the LOI instructions, you will need a proposalCENTRAL account. If you don't already have one, go to proposalCENTRAL by clicking the button below, then click the "Create an Account" link, which is located in the top right corner of the page.
    • Domestic, Canadian, non-profit, public and private institutions
    • OREF requires an Orthopaedic Surgeon in the role of PI or co-PI collaborating with a PhD
    • A PhD may serve as the principal investigator (PI) if an orthopaedic surgeon serves as co-PI
    Deadline to submit LOI has passed
    Nov 13, 2017, 10:59 PM
  • OREF and TAF Innovative and Accelerated Protocols For Rehabilitation of Orthopedic Injuries Research Grant

    $50,000 over a one-year grant period
    • The Orthopaedic Research and Education Foundation and The Aircast Foundation (TAF) solicit investigator-initiated research proposals focused on Innovative and accelerated protocols for rehabilitation of orthopedic injuries.
    • OREF strongly encourages the submission of well-crafted basic, translational and clinical studies.
    • Clinical relevance must be clearly noted in the abstract and specific aims and be obvious from the title and the study design.All proposed projects are should generate results that have a practical application. It is expected that upon completion of the proposed project, the principal investigator will be well poised to pursue NIH/DOD or the equivalent large-scale funding to continue to advance the area of research.
    • NOTE: Letters of Intent—The first step in applying for this grant is to submit a Letter of Intent (LOI), following the instructions provided on ProposalCENTRAL. All properly submitted LOIs will be reviewed by OREF. If your LOI is selected to advance, you will be invited to complete a full proposal. LOIs are due November 13, 2017 by 10:59 p.m. CDT. Applicants invited to submit full proposals will be notified on Wednesday, December 13, 2017 by 10:59 p.m. U.S. Central Time
    • To Access the LOI instructions, you will need a proposalCENTRAL account. If you don't already have one, go to proposalCENTRAL by clicking the button below, then click the "Create an Account" link, which is located in the top right corner of the page.
    • Applications may be submitted by domestic and Canadian, non-profit, public and private institutions of higher education, such as hospitals, medical schools, universities, and colleges.
    • The principal investigator (PI) must be an orthopaedic surgeon or a full-time researcher (e.g., PhD, DVM, DO).  The orthopaedic surgeon must be licensed to practice in and work in an institution in the the United States.
    • A PhD serving as PI or co-PI must hold a primary or secondary faculty appointment in an orthopaedic department. A letter from the department chair confirming this appointment is required and must be uploaded in the appendix section.
    • The orthopaedic surgeon must provide a statement on time to be allocated to the project indicating percent of average time allocated and how time will be spent.
    • The PI must be a new investigator.  A new investigator is classified as an individual who has not received an R01 National Institutes of Health (NIH) grant or its equivalent (e.g., VA, DOD, NSF) as a PI.
    • Applicants are limited to one submission as PI or co-PI to OREF per cycle regardless of the category. The same project may not be submitted in multiple categories, even if the PI is different. The principal investigator may receive only one OREF grant of each type during his/her lifetime.
    Deadline to submit LOI has passed
    Nov 13, 2017, 10:59 PM
  • OREF Total Joint Replacement Grant in Honor of Dr. Jorge O. Galante, MD

    $300,000 over a three-year grant period
    OREF thanks everyone who contributed to the Galante Mentor Campaign for making this grant possible.
    • OREF encourages investigator-initiated research proposals focused on total joint replacement. Areas of research focus may include: New surgical techniques, devices, joint implant designs, joint implant materials, or the biology of disease and repair.
    • OREF strongly encourages the submission of well-crafted basic, translational and clinical studies. Clinical relevance must be clearly noted in the abstract and specific aims and be obvious from the title and the study design.
    • All proposed projects are should generate results that have a practical application. It is expected that upon completion of the proposed project, the principal investigator will be well poised to pursue NIH/DOD or the equivalent large-scale funding to continue to advance the area of research.
    • NOTE: Letters of Intent—The first step in applying for this grant is to submit a Letter of Intent (LOI), following the instructions provided on proposalCENTRAL. All properly submitted LOIs will be reviewed by OREF. If your LOI is selected to advance, you will be invited to complete a full proposal. LOIs are due November 13, 2017 by 10:59 p.m. CDT. Applicants invited to submit full proposals will be notified on Wednesday, December 13, 2017 by 10:59 p.m. U.S. Central Time
    • To Access the LOI instructions, you will need a proposalCENTRAL account. If you don't already have one, go to proposalCENTRAL by clicking the button below, then click the "Create an Account" link, which is located in the top right corner of the page.  
    • Applications may be submitted by domestic and Canadian, non-profit, public and private institutions of higher education, such as hospitals, medical schools, universities, and colleges.
    • The principal investigator (PI) must be an orthopaedic surgeon or a full-time researcher (e.g., PhD, DVM, DO).  The orthopaedic surgeon must be licensed to practice in and work in an institution in the the United States.
    • A PhD serving as PI or co-PI must hold a primary or secondary faculty appointment in an orthopaedic department. A letter from the department chair confirming this appointment is required and must be uploaded in the appendix section.
    • The orthopaedic surgeon must provide a statement on time to be allocated to the project indicating percent of average time allocated and how time will be spent.
    • The PI must be a new investigator.  A new investigator is classified as an individual who has not received an R01 National Institutes of Health (NIH) grant or its equivalent (e.g., VA, DOD, NSF) as a PI.
    • Applicants are limited to one submission as PI or co-PI to OREF per cycle regardless of the category. The same project may not be submitted in multiple categories, even if the PI is different. The principal investigator may receive only one OREF grant of each type during his/her lifetime.
    Deadline to submit LOI has passed
    Nov 13, 2017, 10:59 PM
  • OREF/Goldberg Arthritis Research Grant

    $50,000 grant (Directed program)
    • Encourages new investigators by providing seed and start-up funding for promising research projects that address issues related to the treatment of arthritis with an emphasis on arthroplasty. 
    • Clinical relevance must be clearly noted in the abstract and specific aims, and be obvious from the title and the study design.
    • To Access the Request for Application, you will need a proposalCENTRAL account. If you don't already have one, go to proposalCENTRAL by clicking the button below, then click the "Create an Account" link, which is located in the top right corner of the page.
    • PI or Co-PI must be an orthopaedic surgeon.
    • PhDs and DVMs are eligible if affiliated with an orthopaedic department and working with an orthopaedic surgeon.
    The application period is closed.
    Sep 13, 2016, 10:59 PM
  • OREF Perioperative Surgical and Medical Home Patient Safety Research Grant

    $135,000 over a two year grant period
    • (OREF), in partnership with the American Society of Anesthesiologists (ASA), the Foundation for Anesthesia Education and Research (FAER), the Anesthesia Patient Safety Foundation (APSF), the American Academy of Orthopaedic Surgeons (AAOS) and the Cigna Foundation, encourages proposals in support of high quality research that addresses the perioperative surgical and medical home as they relate to patient safety in orthopaedics.
    • Well-crafted translational and clinical studies that address a culture of safety, team communication, effective communication with patients, appropriateness of tests and treatments, decreased surgeon-to-surgeon variation and other areas of focus are strongly encouraged.
    • Multidisciplinary research activity is encouraged, and OREF requires an Orthopaedic Surgeon in the role of PI or co-PI collaborating with an Anesthesiologist in order to foster the application of a full range of expertise, approaches, technologies and creativity. The Anesthesiologist may serve as the principal investigator (PI) if an orthopaedic surgeon serves as the Co-PI.
    • The orthopaedic surgeon must be licensed to practice in the United States and working in an institution in the U.S. The Orthopaedic Surgeon must be a new investigator. A new investigator is classified as an individual who has not received an R01 National Institutes of Health (NIH) grant or its equivalent (e.g., VA, DOD, and NSF, etc.) as a PI.
    • The Anesthesiologist must be an early stage investigator. An early stage investigator has completed his/her training within 10 years of medical residency and has not received an NIH R01 grant or secured independent funding from other large scale funders in the role of PI (e.g. DOD, NSF, VA, AHRQ, etc).
    • Applications may be submitted by domestic non-profit, public and private institutions of higher education, such as hospitals, medical schools, universities and colleges.
    The application period is closed.
    Mar 14, 2017, 12:00 AM
  • OREF/Stryker Robotic-Assisted Surgery for Primary Total Knee Arthroplasty Prospective Clinical Research Grant

    $90,000 over a two year grant period
    • OREF, in partnership with Stryker, encourages proposals in support of cutting edge research that focuses on robotic-assisted surgery for primary total knee arthroplasty.
    • Well-crafted clinical studies that seek to quantify robotic-assisted patient outcomes in knee arthroplasty are strongly encouraged.
    • Clinical relevance must be clearly noted in the abstract and specific aims and be obvious from the title and the study design.
    • Proposed projects are expected to generate results that have a practical application.
    • The Principal Investigator must be a new investigator.  A new investigator is classified as an individual who has not received an R01 National Institutes of Health (NIH) grant or its equivalent (e.g., VA, DOD, and NSF, etc.) as a PI.  New investigators who have demonstrated a sustained interest in research and excellence in their training are encouraged to apply.
    • Applications may be submitted by domestic or Canadian non-profit, public and private institutions of higher education, such as hospitals, medical schools, universities, and colleges.    
    • PI or co-PI must be an orthopaedic surgeon licensed to practice in the United States and working in an institution in the U.S.
    • PhDs or DVMs are eligible if working in or holding a primary or secondary appointment at an institution/orthopaedic department in the United States or Canada.
    The application period is closed.
    Mar 30, 2017, 09:59 PM
  • OREF Clinical Research Grant in Cellular Therapy in honor of James Urbaniak, MD in Collaboration with National Stem Cell Foundation (NSCF)

    $800,000 over a three-year period

    OREF, in partnership with the National Stem Cell Foundation (NSCF), encourages proposals in support of cutting edge research that focuses on adult stem cell (e.g., mesenchymal or adipose-derived) therapies.

    Highlighted areas of research focus include the following, although other areas of stem cell therapy may be considered:

    • Stem cell therapy approaches for treating musculoskeletal conditions including but not limited to bone, cartilage, intervertebral disc, tendon, ligament, meniscus, muscle, etc.
    • Tissue-specific or adult stem cell and related technology therapies (e.g., mesenchymal, adipose-derived, or muscle stem cells).
    • Advancing the development of tissue-engineering, regenerative medicine, cellular, or pharmacologic technologies that focus on stem cell therapies for late stage translational or early stage clinical studies.
    • Prospective, randomized, and controlled clinical trial to prove or disprove the efficacy of a stem cell therapy for musculoskeletal conditions.
    • Clinical relevance must be clearly noted in the abstract and specific aims and be obvious from the title and the study design.
    • Proposed projects are expected to generate results that have a practical application.
    • Applications may be submitted by domestic or Canadian non-profit, public and private institutions of higher education, such as hospitals, medical schools, universities, and colleges.
    • If the PrinciaI Investigator (PI) is an orthopaedic surgeon, he/she must hold a primary appointment in an orthopaedic surgery department, work in an institution in the U.S. or Canada, and be licensed to practice in the United States. If the PI is a PhD or DVM, he/she must hold a primary or secondary appointment at an institution/orthopaedic department in the U.S. or Canada. A letter from the department chair confirming the appointment is also required.
    • If the PI is an orthopaedic surgeon, he or she must provide a statement on time to be allocated to research, indicating percent of time allocated to this project and how time will be spent.

    NOTE: The first step in applying for this grant is to submit a Letter of Intent (LOI), following the instructions provided on ProposalCentral. All properly submitted LOIs will be reviewed by OREF. If your LOI is selected to advance, you will be invited to complete a full proposal.

    The deadline for submitting an LOI has passed. Applicants invited to submit full proposals will be notified on Tuesday, June 5, 2017 by 10:59 p.m. U.S. Central Time

    The LOI deadline has passed.
    May 2, 2017, 04:59 PM
  • OREF/Musculoskeletal Tumor Society Clinical Research Grant in Orthopaedic Oncology

    $100,250 grant ($50,125 per year, directed program)
    • OREF in partnership with the Musculoskeletal Tumor Society (MSTS) offers grants to clinician researchers focused on oncology (cancer).
    • Encourages promising research that will yield clinical outcomes for patients.
    • MSTS clinical research priorities focus on randomized trials.
    • PI or Co-PI must be an orthopaedic surgeon.
    • PhDs and DVMs are eligible if affiliated with an orthopaedic department and working with an orthopaedic surgeon.
    • PI or Co-PI must be an MSTS member in good standing.
    The application period is closed.
    Jan 15, 2016, 12:00 AM
  • OREF & Orthopaedic Trauma Association Trauma Research Grant in collaboration with Society of Military Orthopaedic Surgeons, DePuy Synthes, and Zimmer Biomet

    $289,000 over a two-year grant period
    •  OREF, in partnership with the Orthopaedic Trauma Association (OTA), encourages investigator-initiated research proposals focusing on Orthopaedic Trauma. For a list of suggested trauma topics, please view the application on proposalCENTRAL.
    • Clinical relevance must be clearly noted in the abstract and specific aims, and be obvious from the title and study design.
    • PI must be an Orthopaedic Surgeon licensed to practice in the United States and working at an institution in the United States or Canada.
    • PhDs or DVMs are eligible if working in or holding a primary appointment at an institution/orthopaedic department in the United States or Canada.
    The application period is closed.
    Dec 15, 2016, 12:00 AM

Have a question for the OREF Grants team?
Submit a question here or email us at grants@oref.org.